GRO-gamma (CXCL3)

CAT: 0209-100-033SSize: 2 µgDry Ice: NoHazardous: No
CAT#:0209-100-033SSize:2 µg
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Description
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant human GRO-γ is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Synonyms
CXCL3; GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b
NCBI Gene ID
2921
UniProt
P19876
Accession Number
NP_002081.2
Accession Number mRNA
NM_002090.2
Chromosomal Location
4q21
Reactivity
Human
Cross Reactivity
Hamster, Human, Mouse
Sequence
ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml.
Length
73
Form
Lyophilized
Molecular Weight
7.9 kDa
Host or Source
E. coli

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