GRO-beta/MIP-2

• Description :

  All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

• Synonyms :

  Cxcl2; Mip-2; Scyb2

• NCBI Gene ID :

  114105

• UniProt :

  P30348

• Accession Number :

  NP_446099

• Accession Number mRNA :

  NM_053647

• Chromosomal Location :

  14p22

• Reactivity :

  Rat

• Cross Reactivity :

  Human, Mouse, Rat

• Sequence :

  VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN

• Endotoxin :

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity :

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity :

  Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

• Length :

  73

• Form :

  Lyophilized

• Molecular Weight :

  7.9 kDa

• Host or Source :

  E. coli