Gp130

CAT: 0209-101-M441Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M441Size:50 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
Synonyms
IL6ST; CD130; GP130; CDW130; IL-6RB
NCBI Gene ID
3572
UniProt
P40189
Accession Number
NP_786943.1
Accession Number mRNA
NM_175767.2
Chromosomal Location
5q11.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human gp 130
Clone
(#9X23)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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