FGFR-3 neutralizing antibody

CAT: 0209-500-002Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-500-002Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.
Synonyms
FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX
NCBI Gene ID
2261
UniProt
P22607
Accession Number
NP_000133
Accession Number mRNA
NM_000142
Chromosomal Location
4p16.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Highly purified human sFGFR-3
Clone
Recombinant IG
Purification Method
Ion exchange chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
Lyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C.
Host or Source
E. coli
Isotype
Fab-Fragment

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