FGFR-3

CAT: 0209-103-M529Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M529Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N terminal signal peptide, three immunoglobulin (Ig) like domains, an acid box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine kinase domain.
Synonyms
Fibroblast growth factor receptor 3, FGFR-3, Heparin-binding growth factor receptor, CD333
NCBI Gene ID
14184
UniProt
Q61851
Accession Number
NP_001156687.1
Accession Number mRNA
NM_001359036.1
Reactivity
Anti-Mouse
Target Antigen
Mouse recombinant protein FGF R3
Clone
(#7M13)
Applications
N/B
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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