Endomucin Recombinant Protein
CAT:
209-S01-M64
Size:
20 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Endomucin Recombinant Protein
- Description: Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively. The sequence corresponds to Glu20 to Ser190. A 6x His-tag is fused to the C-terminal end of the recombinant mouse soluble Endomucin.
- Synonyms: Endomucin-1/2, Mucin-14, Muc-14
- CAS Number: 9000-83-3
- NCBI Gene ID: 59308
- UniProt: Q9R0H2
- Accession Number: NP_001156994.1
- Accession Number mRNA: NM_001163522.1
- Gene Location: 3 G3; 3
- Host: E. coli
- Origin Species: Mouse
- Species Reactivity: Mouse
- Tag: His-Tag
- Sequence: EDGKDVQNDSIPTPAETSTTKASVTIPGIVSVTNPNKPADGTPPEGTTKSDVSQTSLVTTINSLTTPKHEVGTTTEGPLRNESSTMKITVPNTPTSNANSTLPGSQNKTENQSSIRTTEISVTTQLLDALPKITATSSASLTTAHTMSLLQDTEDRKIATTPSTTPSYSSTRHHHHHH
- Detection Range: Data not available.
- Purity: > 95% by SDS-PAGE
- Length: 191
- Form: Lyophilized
- Buffer: 10mM NaP, pH 7.0
- Reconstitution: The lyophilized mouse sEndomucin is soluble in water and most aqueous buffers; it should be reconstituted in water or PBS to a concentration of not lower than 100µg/ml.
- Molecular Weight: 18.78 kDa
- Shipping Conditions: Room Temperature
- Storage Conditions: The material is stable for greater than six months at -20° C to -70° C. After the first thawing it is recommended to aliquote the material, because repeated freeze-thaw cycles will decrease the activity.