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Endomucin

CAT: 0209-S01-064Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0209-S01-064Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.
Synonyms
Endomucin-2, Gastric cancer antigen Ga34, Mucin-14
NCBI Gene ID
51705
UniProt
Q9ULC0
Accession Number
NP_001153166.1
Accession Number mRNA
NM_001159694.1
Chromosomal Location
4q24
Reactivity
Human
Cross Reactivity
Human
Label
His-Tag
Sequence
MGSSHHHHHHSSGLVPRGSHMGSHMNSTGVLEAANNSLVVTTTKPSITTPNTESLQKNVVTPTTGTTPKGTITNELLKMSLMSTATFLTSKDEGLKATTTDVRKNDSIISNVTVTSVTLPNAVSTLQSSKPKTETQSSIKTTEIPGSVLQPDASPSKTGTLTSIPVTIPENTSQSQVIGTEGGKNASTSATSRSYSS
Assay Protocol
The lyophilized human soluble Endomucin is soluble in water and most aqueous buffers; it should be reconstituted in water or PBS to a concentration of not lower than 100 µg/ml.
Purity
> 95% by SDS-PAGE
Bioactivity
Data not available.
Length
197
Form
Lyophilized
Buffer
10mM NaP, pH 7.0
Reconstitution
Water
Molecular Weight
20.4 kDa
Storage Conditions
The material is stable for greater than six months at -20° C to -70° C. After the first thawing it is recommended to aliquote the material, because repeated freeze-thaw cycles will decrease the activity.
Host or Source
E. coli

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