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Emilin-1

CAT: 0209-103-M80Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M80Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.
Synonyms
Gp115; AW229038; BB105748; EMILIN-1; 5830419M17Rik; elastin microfibril interface located protein 1
NCBI Gene ID
100952
UniProt
Q99K41
Accession Number
NP_598679.1
Accession Number mRNA
NM_133918.2
Chromosomal Location
5 B1; 5
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse Emilin-1
Clone
(#C11A8)
Applications
WB, IHC (F)
Purification Method
Protein-G purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: use at 2-10 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rat