EG-VEGF

• Description:

  EG-VEGF is a secreted angiogenetic mitogen growth factor expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF induces proliferation and migration fenestration (formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. The murine EG-VEGF gene codes for a 105 amino acid polypeptide containing an N-terminal signal sequence of 19 amino acids. Recombinant murine EG-VEGF is a 9.6 kDa protein consisting of 86 amino acid residues and ten cysteine residues that potentially form five pairs of intra-molecular disulfide bonds.

• Synonyms:

  Endocrine Gland-derived Vascular endothelial growth factor, Prokineticin 1, PROK1

• NCBI Gene ID:

  246691

• UniProt:

  Q14A28

• Accession Number:

  NP_001037847.1

• Accession Number mRNA:

  NM_001044382.1

• Chromosomal Location:

  3F2.3

• Reactivity:

  Mouse

• Cross Reactivity:

  Mouse

• Sequence:

  AVITGACERD IQCGAGTCCA ISLWLRGLRL CTPLGREGEE CHPGSHKIPF LRKRQHHTCP CSPSLLCSRF PDGRYRCFRD LKNANF

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Data not available.

• Length:

  105

• Form:

  Lyophilized

• Molecular Weight:

  9.6 kDa

• Host or Source:

  E. coli