EDG-1

• Description:

  S1P1, also known as EDG1, is a member of the endothelial differentiation gene family. It is a high affinity G proteincoupled receptor for the bioactive lipid, Sphingosine1phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.

• Synonyms:

  S1PR1; EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362

• NCBI Gene ID:

  1901

• UniProt:

  P21453

• Accession Number:

  NP_001391.2

• Accession Number mRNA:

  NM_001400.4

• Chromosomal Location:

  1p21

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human EDG-1 protein

• Clone:

  (#21L9)

• Applications:

  WB, IHC (P), FC

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1