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DMP-1

CAT: 0209-101-M579Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M579Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dentin matrix acidic phosphoprotein 1 is a protein that in humans is encoded by the DMP1 gene. DMP1 is an extracellular matrix protein and a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family (other members being DSPP, IBSP, MEPE, and SPP1) . This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional Arg-Gly-Asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes.
Synonyms
Dentin matrix acidic phosphoprotein 1, DMP-1; Dentin matrix protein 1
NCBI Gene ID
1758
UniProt
Q13316
Accession Number
NP_001073380.1
Accession Number mRNA
NM_001079911.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human DMP-1
Clone
(#35K29)
Applications
E
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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