DMP-1

• Description:

  Dentin matrix acidic phosphoprotein 1 is a protein that in humans is encoded by the DMP1 gene. DMP1 is an extracellular matrix protein and a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family (other members being DSPP, IBSP, MEPE, and SPP1) . This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional Arg-Gly-Asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes.

• Synonyms:

  Dentin matrix acidic phosphoprotein 1, DMP-1; Dentin matrix protein 1

• NCBI Gene ID:

  1758

• UniProt:

  Q13316

• Accession Number:

  NP_001073380.1

• Accession Number mRNA:

  NM_001079911.2

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant Human DMP-1

• Clone:

  (#35K29)

• Applications:

  E

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1