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Dihydrofolate Reductase

CAT: 0209-101-M365Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M365Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dihydrofolate reductase (DHFR), also called dihydrofolic acid reductase, are enzymes that hydrogenate folic acid to dihydrofolic acid (DHF) and DHF to tetrahydrofolic acid (THF) . These reactions activate the vitamin folic acid and are essential for nucleotide biosynthesis in all living organisms. In humans, DHFR is found in all tissue types. Mutations at the DHFR gene can cause dihydrofolate reductase deficiency, and this megaloblastic anemia.
Synonyms
Dihydrofolate reductase
NCBI Gene ID
1719
UniProt
P00374
Accession Number
NP_000782.1
Accession Number mRNA
NM_000791.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Dihydrofolate Reductase
Clone
(#24A8)
Applications
WB, IHC (P), ICC
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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