CXCL9 (MIG)

• Description:

  MIG or CXCL9 , a CXC chemokine, is produced by IFN stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant human MIG is an 11.7 kDa protein containing 103 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

• Synonyms:

  C-X-C motif chemokine 9; CXCL9; CMK; MIG; HuMIG; SCYB9; crg-10; Small-inducible cytokine B9; Monokine induced by interferon-gamma

• NCBI Gene ID:

  4283

• UniProt:

  Q07325

• Accession Number:

  NP_002407.1

• Accession Number mRNA:

  NM_002416.1.

• Chromosomal Location:

  4q21

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human CXCL-9

• Clone:

  (#7F11)

• Applications:

  WB, IHC (F), FC, N

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Bioactivity:

  IHC (frozen) 1:20-100; FC 1:50-200; WB 1:500-1000; Neutralization of CXCL9 mediated bioreactivity

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1