CXCL4 (PF-4)

• Description:

  PF-4 (or CXCL4) is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.

• Synonyms:

  Pf4; Cxcl4; Scyb4

• NCBI Gene ID:

  56744

• UniProt:

  Q9Z126

• Accession Number:

  NP_064316.1

• Accession Number mRNA:

  NM_019932.4

• Chromosomal Location:

  5 E1; 5

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Mouse recombinant CXCL4

• Clone:

  (#14M15)

• Applications:

  WB, IHC

• Purification Method:

  Protein G/A chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2