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CLEC9a (DNGR-1)

CAT: 0209-101-M232Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M232Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CLEC9A, a group V C-type lectin-like receptor, is located in the “Dectin-1 cluster” of related receptors, which are encoded within the natural killer (NK) -gene complex. Expression of human CLEC9A is highly restricted in peripheral blood, being detected only on BDCA3+ dendritic cells and on a small subset of CD14+CD16- monocytes. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. CLEC9A possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase, and it was shown, using receptor chimeras, that this receptor can induce proinflammatory cytokine production.
Synonyms
C-type lectin domain family 9 member A, CD370
NCBI Gene ID
283420
UniProt
Q6UXN8
Accession Number
NP_997228.1
Accession Number mRNA
NM_207345.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human CLEC9a
Clone
(#30L2)
Applications
FC
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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Alternative Products

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