CD45

• Description:

  CD45 is a transmembrane protein tyrosine phosphatase. It is expressed at high levels on the cell surface of all nucleated hematopoietic cells and their precursors. Alternative splicing of CD45 mRNA results in the expression of several distinct isoforms that are differentially expressed in cells of different lineages and activation states.

• Synonyms:

  Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; Lymphocyte antigen 5; Ly-5; T200

• NCBI Gene ID:

  19264

• UniProt:

  S4R1Mo

• Accession Number:

  NP_001255215

• Accession Number mRNA:

  NM_001268286.1

• Chromosomal Location:

  1 E4; 1 74.0 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Cell lysates of mouse leukocytes

• Clone:

  (#5C16)

• Applications:

  IHC (P), IP

• Purification Method:

  Protein G/A chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS (sterile)

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2