CD36 (SR-B3)

• Description:

  CD36, also known as scavenger receptor class B member 3 (SR-B3), platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, and fatty acid translocase (FAT), is a broadly-expressed integral membrane glycoprotein that has multiple physiological functions. As a member of the scavenger receptor family, CD36 is a multi-ligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands. Upon ligand binding, CD36 transduces signals that mediate a wide range of pro-inflammatory cellular responses.

• Synonyms:

  CD36; FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10

• NCBI Gene ID:

  948

• UniProt:

  P16671

• Accession Number:

  NP_001001548.1

• Accession Number mRNA:

  NM_001001548.2

• Chromosomal Location:

  7q11.2

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant CD36 EC domain

• Clone:

  (#7K67)

• Applications:

  FC, Capture AB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2