CD31/PECAM-1

• Description:

  The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions, on T cell subsets, and to a lesser extent, on platelets and most leukocytes. CD31 is required for the transendothelial migration of leukocytes through the intercellular spaces between vascular endothelial cells.

• Synonyms:

  PECAM-1

• NCBI Gene ID:

  18613

• UniProt:

  Q08481

• Accession Number:

  NP_032842.2

• Accession Number mRNA:

  NM_008816.2

• Chromosomal Location:

  11 E1; 11

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Mouse endothelial membrane protein

• Clone:

  (#1D12)

• Applications:

  IHC

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS (sterile)

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2a