CD3e

CAT: 0209-103-M516Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-103-M516Size:50 µg
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Description
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women
Synonyms
T-cell surface antigen T3/Leu-4 epsilon chain
NCBI Gene ID
12501
UniProt
P22646
Accession Number
NP_031674.1
Accession Number mRNA
NM_007648.4
Reactivity
Anti-Mouse
Target Antigen
Recombinant mouse CD3e
Clone
(#1T29)
Applications
FC, IP
Host or Source
Hamster
Isotype
IgG

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