BCMA Recombinant Protein

CAT:

209-100-131S

Size:

5 µg

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Description: BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain. Recombinant soluble BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein.
Synonyms: TNFRSF17; BCM; BCMA; CD269
CAS Number: 9000-83-3
NCBI Gene ID: 608
UniProt: Q02223
Accession Number: NP_001183
Accession Number mRNA: NM_001192
Gene Location: 16p13.1
Host: E. coli
Origin Species: Human
Species Reactivity: Human
Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Detection Range: Data not available.
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Purity: > 98% by SDS-PAGE & HPLC analyses
Length: 50
Form: Lyophilized
Molecular Weight: 5.3 kDa
Shipping Conditions: Room Temperature

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