BCA-1 Recombinant Protein

BCA-1 Recombinant Protein

• Description: BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3 kDa protein containing 87 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
• Synonyms: CXCL13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13
• CAS Number: 9000-83-3
• NCBI Gene ID: 10563
• UniProt: O43927
• Accession Number: NP_006410.1
• Accession Number mRNA: NM_006419.2
• Gene Location: 4q21
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human
• Sequence: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP
• Detection Range: The biological activity of human BCA-1 was determined by chemotaxis assay using human B cells. Significant chemotaxis was achieved at a concentration range of 1.0-10 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 87
• Form: Lyophilized
• Molecular Weight: 10.3 kDa
• Shipping Conditions: Room Temperature