BAFF (Animal Free) Recombinant Protein
CAT:
209-100-002-AF
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BAFF (Animal Free) Recombinant Protein
- Description: BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors, TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant Human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.
- Synonyms: TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF22
- CAS Number: 9000-83-3
- NCBI Gene ID: 10673
- UniProt: Q9Y275
- Accession Number: NP_006564.1
- Accession Number mRNA: NM_006573.4
- Gene Location: 13q32-q34
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL
- Detection Range: Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 µg/ml.
- Endotoxin: < 0.01 ng/µg of protein (<0.1EU/µg)
- Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.
- Length: 153
- Form: Lyophilized
- Molecular Weight: 17.0 kDa
- Shipping Conditions: Room Temperature