BACE-1

CAT: 0209-101-M227Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M227Size:50 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cleavage of amyloid precursor protein (APP) into 40 or 42 amino acid amyloid β (aβ) peptides is a result of the action of two proteases β- and γ-secretase. The beta-site APP cleaving enzyme, or BACE-1, is a transmembrane aspartic protease that is localized in the Golgi and endosomes. Low levels of BACE-1 mRNA are found in most adult tissues with a higher level of expression in pancreas.
Synonyms
BACE1; ASP2; BACE; HSPC104
NCBI Gene ID
23621
UniProt
P56817
Accession Number
NP_036236.1
Accession Number mRNA
NM_012104.4
Chromosomal Location
11q23.2-q23.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human recombinant BACE-1 (EC domain)
Clone
(#6J26)
Applications
WB, IHC (P)
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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