Apo-SAA1

• Description:

  Recombinant human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues. Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL) . The level of Apo-SAA usually is 1-5 μg/ml in plasma. It increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. The human SAA gene codes for a 122 amino acid non-glycosylated polypeptide, which contains an 18 amino acid N-terminal sequence.

• Synonyms:

  Apo-SAA1

• NCBI Gene ID:

  6288

• UniProt:

  P0DJI8

• Accession Number:

  NP_000322.2

• Accession Number mRNA:

  NM_000331.4

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Sequence:

  MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

• Length:

  105

• Form:

  Lyophilized

• Molecular Weight:

  ~11.7 kDa

• Host or Source:

  E. coli