Rabbit Anti-Human Adiponectin Polyclonal Antibody
CAT:
209-102-P102
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rabbit Anti-Human Adiponectin Polyclonal Antibody
- Description: Adiponectin is an adipose-derived secreted protein containing 226 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-α and class A scavenger receptor in macrophages).
- Synonyms: Acrp-30, GBP-28, APM-1, Gelatin-binding protein, AdipoQ
- NCBI Gene ID: 9370
- UniProt: Q15848
- Accession Number: NP_001171271
- Accession Number mRNA: NM_001177800
- Gene Location: 3q27
- Host: Rabbit
- Origin Species: Human
- Species Reactivity: Human
- Target Antigen: Hi-5 Insect cells derived Recombinant Human Adiponectin (#100-121)
- Isotype: IgG
- Clone: Rabbit IgG
- Validated Applications: WB, ELISA
- Purification Method: Antigen-affinity purified
- Form: Lyophilized
- Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.