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Medroxyprogesterone acetate

CAT: 0804-HY-B0469-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0469-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].
CAS Number
71-58-9
Product Name Alternative
Medroxyprogesterone 17-acetate; Farlutin
UNSPSC
12352211
Hazard Statement
H351, H413
Target
Androgen Receptor; Endogenous Metabolite; Glucocorticoid Receptor; Progesterone Receptor
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/Medroxyprogesterone-acetate.html
Purity
99.88
Solubility
DMSO : 10 mg/mL (ultrasonic) |Ethanol : 6.25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL
Smiles
CC(O[C@@]([C@]12C)(CC[C@@]1([H])[C@@](C[C@H](C)C3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC2)C(C)=O)=O
Molecular Formula
C24H34O4
Molecular Weight
386.52
Precautions
H351, H413
References & Citations
[1]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61 (1-2) :171-80.|[2]Simoncini T, et al. Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells. Endocrinology. 2004 Dec;145 (12) :5745-56. |[3]Smith D, et al. Pharmacokinetics and bioavailability of medroxyprogesterone acetate in the dog and the rat. Biopharm Drug Dispos. 1993 May;14 (4) :341-55. |[4]Bernardi F, et al. Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels. Neuroendocrinology. 2006;83 (5-6) :348-59.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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