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JZP-430

CAT: 0804-HY-101457-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101457-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL) [1].
CAS Number
1672691-74-5
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/jzp-430.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1=NSN=C1N2CCOCC2)N(C3CCCCCCC3)C
Molecular Formula
C16H26N4O3S
Molecular Weight
354.47
References & Citations
[1]Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10 (2) :253-65.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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BA7955-10JZP-430
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A20413-10JZP-430 10mg
A20413-5JZP-430 5mg
A20413-200JZP-430 200mg
A20413-100JZP-430 100mg
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A20413-25JZP-430 25mg
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