Picamilon

CAT: 0804-HY-107482-02Size: 500 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-107482-02Size:500 mg

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Description

Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan -induced diabetes mellitus in rats[1][2][3].

CAS Number

34562-97-5

Product Name Alternative

Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/picamilon.html

Concentration

10mM

Purity

99.37

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(CCCNC(C1=CN=CC=C1)=O)=O

Molecular Formula

C10H12N2O3

Molecular Weight

208.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Mirzoian RS, et al. Vliianie pikamilona na krovosnabzhenie kory i mikrotsirkuliatsiiu v sisteme pial'nykh arteriol [Effect of pikamilon on the cortical blood supply and microcirculation in the pial arteriole system]. Biull Eksp Biol Med. 1989 May;107 (5) :581-2. Russian. |[2]Denisenko, et al. Effects of Picamilon and Isopicamilon on the Formation of Picrotoxin-Induced Convulsive Activity in Rats. Neurophysiology 46, 284–287 (2014) .

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Chemical Information

4-((3-Pyridinylcarbonyl)amino)butanoic acid

used in treatment of migraine

CAS Number	34562-97-5
PubChem CID	60608
IUPAC Name	4-(pyridine-3-carbonylamino)butanoic acid
Molecular Formula	C10H12N2O3
Molecular Weight	208.21
XLogP	-0.4
Topological Polar Surface Area	79.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Heavy Atom Count	15
Formal Charge	0
Complexity	231

SMILES

C1=CC(=CN=C1)C(=O)NCCCC(=O)O

InChI

InChI=1S/C10H12N2O3/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14)

InChIKey

NAJVRARAUNYNDX-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 34562-97-5

CID: 60608

Formula: C10H12N2O3

MW: 208.21

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	208.21
XLogP3	-0.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	208.08479225
Monoisotopic Mass	208.08479225
Topological Polar Surface Area	79.3 Å²
Heavy Atom Count	15
Formal Charge	0
Complexity	231
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Picamilon

Chemical Information

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