Regorafenib-d3

CAT: 0804-HY-10331S-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10331S-01Size:5 mg
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Description
Regorafenib-d3 (BAY 73-4506-d3) is a deuterium labeled Regorafenib (HY-10331) . Regorafenib is a multi-targeted receptor tyrosine kinase inhibitor[1].
CAS Number
[1255386-16-3]
Product Name Alternative
BAY 73-4506-d3
UNSPSC
12352005
Target
Autophagy; PDGFR; Raf; RET; VEGFR
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.0
Solubility
10 mM in DMSO|DMSO : 125mg/mL (ultrasonic)
Smiles
O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1)NC([2H])([2H])[2H]
Molecular Formula
C21H12D3ClF4N4O3
Molecular Weight
485.83
References & Citations
[1]Wilhelm SM, et al. Regorafenib (BAY 73-4506) : a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer, 2011, 129 (1), 245-255.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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