Uridine triphosphate (trisodium salt)

Uridine triphosphate (trisodium salt)

• CAS Number: 19817-92-6
• UNSPSC Description: Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors[1][2].
• Target Antigen: Endogenous Metabolite; P2Y Receptor
• Type: Natural Products
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Inflammation/Immunology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/uridine-triphosphate-trisodium-salt.html
• Purity: 97.0
• Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : 75 mg/mL (ultrasonic)
• Smiles: O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(OP(OP([O-])([O-])=O)([O-])=O)(O)=O.[3Na+]
• Molecular Weight: 550.09
• References & Citations: [1]Choi JH, et al. Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor. Pancreas. 2013 May;42(4):680-6.|[2] Lamarca A, et al. Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation. PLoS One. 2014 Jun 6;9(6):e98998.|[3]Yitzhaki S, et al. Uridine-5'-triphosphate (UTP) reduces infarct size and improves rat heart function aftermyocardial infarct. Biochem Pharmacol. 2006 Oct 16;72(8):949-55.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: Phase 3