Nintedanib Dimer Impurity

• Synonyms:

  (3Z,3'Z)-Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))bis(2-oxoindoline-6-carboxylate)

• Hazard Statement:

  Harmful if swallowed

• Purity:

  >95% (HPLC)

• Smiles:

  COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN4CCN(CC(=O)N(C)c5ccc(N\C(=C\6/C(=O)Nc7cc(ccc67)C(=O)OC)\c8ccccc8)cc5)CC4)/c9ccccc9)\C(=O)Nc2c1

• Molecular Formula:

  C56 H52 N8 O8

• Molecular Weight:

  965.061

• InChI:

  InChI=1S/C56H52N8O8/c1-61(41-21-17-39(18-22-41)57-51(35-11-7-5-8-12-35)49-43-25-15-37(55(69)71-3)31-45(43)59-53(49)67)47(65)33-63-27-29-64(30-28-63)34-48(66)62(2)42-23-19-40(20-24-42)58-52(36-13-9-6-10-14-36)50-44-26-16-38(56(70)72-4)32-46(44)60-54(50)68/h5-26,31-32,57-58H,27-30,33-34H2,1-4H3,(H,59,67)(H,60,68)/b51-49-,52-50-

• Additionnal Information:

  IUPAC name: methyl (3Z)-3-[[4-[[2-[4-[2-[4-[[(Z)-(6-methoxycarbonyl-2-oxo-1H-indol-3-ylidene)-phenylmethyl]amino]-N-methylanilino]-2-oxoethyl]piperazin-1-yl]acetyl]-methylamino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C