HAEGT

• UNSPSC Description:

  HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity[1].

• Target Antigen:

  Dipeptidyl Peptidase; GLP Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/HAEGT.html

• Purity:

  98.86

• Solubility:

  H2O

• Smiles:

  O=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)[C@H](CC1=CNC=N1)N

• Molecular Weight:

  513.50

• References & Citations:

  [1]Lisa M Kopcho, et al. Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach. Arch Biochem Biophys. 2005 Apr 15;436(2):367-76.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  852155-81-8