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HAEGT

CAT: 0804-HY-P1230-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1230-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity[1].
CAS Number
852155-81-8
UNSPSC
12352209
Target
Dipeptidyl Peptidase; GLP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/HAEGT.html
Purity
98.86
Solubility
H2O
Smiles
O=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)[C@H](CC1=CNC=N1)N
Molecular Formula
C20H31N7O9
Molecular Weight
513.50
References & Citations
[1]Lisa M Kopcho, et al. Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach. Arch Biochem Biophys. 2005 Apr 15;436 (2) :367-76.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
DPP-4

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