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Viltolarsen

CAT: 0804-HY-132586-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132586-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research[1][2].
CAS Number
2055732-84-6
Product Name Alternative
NS-065/NCNP-01
UNSPSC
12352208
Target
Dystrophin; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/viltolarsen.html
Purity
95.25
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[Viltolarsen]
Molecular Formula
C244H381N113O88P20
Molecular Weight
6924.80
References & Citations
[1]Sohita Dhillon. Viltolarsen: First Approval. Drugs. 2020 Jul;80 (10) :1027-1031. |[2]Naoki Watanabe, et al. NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2018 Dec 7:13:442-449.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 4

Alternative Products

CatalogName
GTR19189460-01Viltolarsen

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