Products for Research Use Only
RegisterLogin

Eicosanedioic acid

CAT: 0804-HY-W034595-02Size: 10 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W034595-02Size:10 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
CAS Number
2424-92-2
UNSPSC
12352203
Hazard Statement
H315, H319
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eicosanedioic-acid.html
Purity
99.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(O)CCCCCCCCCCCCCCCCCCC(O)=O
Molecular Formula
C20H38O4
Molecular Weight
342.51
Precautions
H315, H319
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker

Chemical Information

Eicosanedioic Acid

Icosanedioic acid is an alpha,-dicarboxylic acid that is the 1,18-dicarboxy derivative of octadecane. It has a role as a metabolite. It is a conjugate acid of an icosanedioic acid anion. It derives from a hydride of an icosane.

CAS Number2424-92-2
PubChem CID75502
IUPAC Nameicosanedioic acid
Molecular FormulaC20H38O4
Molecular Weight342.5
XLogP7.5
Topological Polar Surface Area74.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count19
Heavy Atom Count24
Formal Charge0
Complexity272
SMILES
C(CCCCCCCCCC(=O)O)CCCCCCCCC(=O)O
InChI
InChI=1S/C20H38O4/c21-19(22)17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(23)24/h1-18H2,(H,21,22)(H,23,24)
InChIKey
JJOJFIHJIRWASH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Eicosanedioic Acid
CAS: 2424-92-2
CID: 75502
Formula: C20H38O4
MW: 342.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight342.5
XLogP37.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count19
Exact Mass342.27700969
Monoisotopic Mass342.27700969
Topological Polar Surface Area74.6 Ų
Heavy Atom Count24
Formal Charge0
Complexity272
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-140589Acid-PEG4-S-PEG4-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-W517110-01Deltamethric acid
HY-W342979-01Petroselaidic acid
HY-W004260-01Arachidic acid
HY-N0787-01Cryptochlorogenic acid
HY-N1984-01Artemisic acid

Alternative Products

CatalogName
448104-01Eicosanedioic Acid
TRC-E476862-25MGEicosanedioic Acid-d4
1119061-69-6Eicosanedioic Acid, 1- (1,1-Dimethylethyl) 20- (2,5-Dioxo-1-Pyrrolidinyl) Ester
OR1071368-01Acid-apeg6-acid
MBS6083807-01Medronic Acid (Methylenebiphosphonic Acid, Methylenediphosphonic Acid, Methanebisphosphonic Acid, Methanediphosphonic Acid, MDP)
L2500-01Lipoic Acid (Thioctic Acid, (±) -α-Lipoic Acid)
041005Cacodylic Acid (dimethylarsonic acid, dimethylarsinic acid)
MBS641082-01Lipoic Acid (Thioctic Acid, Alpha Lipoic Acid)
275335-01Ethylenediaminediacetic acid dipropionic acid
O8099-01Oxalacetic Acid (Oxaloacetic acid)

Popular Products