TNIK-IN-7

TNIK-IN-7

• CAS Number: 1417795-24-4
• UNSPSC Description: TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/tnik-in-7.html
• Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: N#CC1=CC=C(OC)C(C2=CC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)=C1
• Molecular Weight: 386.45
• References & Citations: [1]Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported