TNIK-IN-3

• Target :

  DAPK|||Wnt/beta-catenin

• Related Pathways :

  Cytoskeletal Signaling|||Stem Cells|||Apoptosis

• Purity :

  0.9956

• Bioactivity :

  TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK) . It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 ?M. Additionally, TNIK-IN-3 demonstrates inhibitory activity against Flt4 (IC50 = 0.030 ?M), Flt1 (IC50 = 0.191 ?M), and DRAK1 (IC50 = 0.411 ?M) . This compound holds potential for carrying out research on colorectal cancer (CRC) [1].

• Smiles :

  Fc1ccc(CN2CCOc3cc(ccc3C2=O)-c2cnc3[nH]ccc3c2)cc1

• Molecular Formula :

  C23H18FN3O2

• Molecular Weight :

  387.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2754265-25-1