TNIK-IN-3

• Target:

  DAPK|||Wnt/beta-catenin

• Related Pathways:

  Cytoskeletal Signaling|||Stem Cells|||Apoptosis

• Purity:

  0.9956

• Bioactivity:

  TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK) . It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 ?M. Additionally, TNIK-IN-3 demonstrates inhibitory activity against Flt4 (IC50 = 0.030 ?M), Flt1 (IC50 = 0.191 ?M), and DRAK1 (IC50 = 0.411 ?M) . This compound holds potential for carrying out research on colorectal cancer (CRC) [1].

• Smiles:

  Fc1ccc (CN2CCOc3cc (ccc3C2=O) -c2cnc3[nH]ccc3c2) cc1

• Molecular Formula:

  C23H18FN3O2

• Molecular Weight:

  387.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2754265-25-1