Ethyl glucuronide

• Description :

  Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite; Toll-like Receptor (TLR)

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ethyl-glucuronide.html

• Purity :

  99.22

• Solubility :

  H2O : 125 mg/mL (ultrasonic)

• Smiles :

  OC([C@@H]1[C@H]([C@@H]([C@@H](O)[C@H](OCC)O1)O)O)=O

• Molecular Formula :

  C8H14O7

• Molecular Weight :

  222.19

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Małkowska A, et al., The influence of caffeine on ethyl glucuronide levels in rat serum and in rat hair. Pharmacol Rep. 2018 Oct;70 (5) :831-836.|[2]Lewis SS, et al., Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain Behav Immun. 2013 May;30:24-32.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [17685-04-0]