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3-Picolylamine

CAT: 0804-HY-Y0047-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0047-01Size:5 g
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Description
3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine. 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses)[2].
CAS Number
3731-52-0
Product Name Alternative
Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine
UNSPSC
12352005
Hazard Statement
H290, H314
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/3-picolylamine.html
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCC1=CC=CN=C1
Molecular Formula
C6H8N2
Molecular Weight
108.14
Precautions
H290, H314
References & Citations
[1]Park Y, et al. Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2019 Sep 23;63 (10) :e01006-19.|[2]BLASCHKO H, et al. Potentiation of the response to histamine by picolylamines. Br J Pharmacol Chemother. 1962 Dec;19 (3) :544-51.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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