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Camlipixant

CAT: 0804-HY-136026-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136026-01Size:1 mg
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Description
Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough[1].
CAS Number
1621164-74-6
Product Name Alternative
BLU-5937
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/camlipixant.html
Concentration
10mM
Purity
99.94
Smiles
O=C(N1C[C@H](CC2=C(C3=C(F)C=C(C(NC)=O)C=C3F)N=C4C=C(C)C=CN42)OCC1)OC
Molecular Formula
C23H24F2N4O4
Molecular Weight
458.46
Precautions
H302, H315, H319
References & Citations
[1]Garceau D, Chauret N. BLU-5937: A selective P2X3 antagonist with potent anti-tussive effect and no taste alteration. Pulm Pharmacol Ther. 2019 Jun;56:56-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

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CatalogName
BA6851-1Camlipixant

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