Products for Research Use Only
RegisterLogin

Docetaxel (Trihydrate) (Standard)

CAT: 0804-HY-B0011AR-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0011AR-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Docetaxel (Trihydrate) (Standard) is the analytical standard of Docetaxel (Trihydrate) . This product is intended for research and analytical applications. Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule?depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of?bcl-2?and?bcl-xL?gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].
CAS Number
148408-66-6
Product Name Alternative
RP-56976 (Trihydrate) (Standard)
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/docetaxel-trihydrate-standard.html
Smiles
O=C(OC(C)(C)C)N[C@H]([C@H](C(O[C@@H]1C(C)=C([C@@H](O)C([C@@]2(C)[C@]([C@@](CO3)(OC(C)=O)[C@@]3([H])C[C@@H]2O)([H])[C@@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[C@@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O
Molecular Formula
C43H59NO17
Molecular Weight
861.93
References & Citations
[1]Attia RT, et al. The chemomodulatory effects of glufosfamide on docetaxel cytotoxicity in prostate cancer cells. PeerJ. 2016 Jun 29;4:e2168.|[2]Che CL, et al. DNA microarray reveals different pathways responding to paclitaxel and docetaxel in non-small cell lung cancer cell line. Int J Clin Exp Pathol. 2013 Jul 15;6 (8) :1538-48.|[3]Obi-Ioka Y, et al. Involvement of Wee1 in the circadian rhythm dependent intestinal damage induced by docetaxel. J Pharmacol Exp Ther. 2013 Oct;347 (1) :242-8.|[4]Li C, et al. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. J Pharm Biomed Anal. 2016 Sep 5;128:286-93.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-B0011A-01Docetaxel (Trihydrate)
HY-B0011AS-01Docetaxel-d5 (trihydrate)
HY-B0011R-01Docetaxel (Standard)
HY-13678AR-01Meropenem (trihydrate) (Standard)
HY-W013075RRutin (trihydrate) (Standard)
HY-B1381ARCefixime (trihydrate) (Standard)
HY-B0467BR-01Amoxicillin (trihydrate) (Standard)
HY-17015R-01Peramivir (trihydrate) (Standard)
HY-B0522BR-01Ampicillin (trihydrate) (Standard)
HY-W010892R-01Scopolamine (hydrobromide trihydrate) (Standard)

Alternative Products

CatalogName
FD29606-01Docetaxel trihydrate
A15070-500Docetaxel Trihydrate 500mg
A15070-250Docetaxel Trihydrate 250mg
447603-01Docetaxel Trihydrate discontinued
A15070-100Docetaxel Trihydrate 100mg
BD164375Docetaxel trihydrate - Bio-X TM
A15070-10mM-DDocetaxel Trihydrate 10mM * 1mL in DMSO
A4394-50Docetaxel

Popular Products