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TGFBR2 Mouse Monoclonal Antibody

CAT: 0013-GTR17694448Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17694448Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-TGFBR2 Antibody (monoclonal, B4H33) . Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Product Name Alternative
AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TbetaR II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta type II receptor; TGFbeta RII; TGFBR2; TGFR 2
UniProt
P37173
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human TGFBR2, different from the related mouse sequence by five amino acids, and from the related rat sequence by eight amino acids.
Target
TGF-beta receptor type-2
Clonality
Monoclonal
Clone
B4H33
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction
Purification
Immunogen affinity purified.
Concentration
500 μg/ml
Dilution
Western blot, 0.25-0.5μg/ml, Human Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human Immunocytochemistry/Immunofluorescence, 5μg/ml, Human Flow Cytometry (Fixed), 1-3μg/1x10^6 cells, Human
Form
Lyophilized
Molecular Weight
70-85 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IF, IHC, WB
Host or Source
Mouse
Preservative
Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Isotype
Mouse IgG2b

UniProtKB · P37173

TGF-beta receptor type-2

TGFR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P37173
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TGFBR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TGFR-2
EC number
2.7.11.30
Processing
Precursor
Secondary accessions
B4DTV5, Q15580, Q6DKT6, Q99474
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Aortic aneurysmCraniosynostosisDisease variantHereditary nonpolyposis colorectal cancer

Biological process

ApoptosisDifferentiationGrowth regulation

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

KinaseReceptorSerine/threonine-protein kinaseTransferase

Domain

SignalTransmembraneTransmembrane helix

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