(E) -Crotonic acid

CAT: 0804-HY-Y1644-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-Y1644-01Size:500 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC 8751 (trans-2-Butenoic acid; trans-Crotonic acid) is an unsaturated carboxylic acid compound containing α, β-unsaturated carboxylic acid groups. NSC 8751 is one of the important analogs for evaluating the safety of fragrance ingredients and is used to evaluate the toxicological properties of compounds with similar structures. When NSC 8751 is applied to local lymph nodes, a 50% concentration does not cause skin sensitization. Structural analogs of NSC 8751 have been shown to be non-genotoxic. trans-Crotonic acid can be used in the preparation of cosmetics and food additives[1][2].
CAS Number
[107-93-7]
Product Name Alternative
(E) -2-Butenoic acid; trans-2-Butenoic acid; trans-Crotonic acid
UNSPSC
12352211
Hazard Statement
H318
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nsc-8751.html
Purity
99.77
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
C/C=C/C(O)=O
Molecular Formula
C4H6O2
Molecular Weight
86.09
Precautions
H318
References & Citations
[1]Api AM, et al. RIFM fragrance ingredient safety assessment 2-methyl-trans-2-butenoic acid, CAS Registry Number 80-59-1. Food Chem Toxicol. 2018 Sep;118 Suppl 1:S1-S7.|[2]Jasicka-Misiak I, et al. Crotonic acid as a bioactive factor in carrot seeds (Daucus carota L.) . Phytochemistry. 2005 Jun;66 (12) :1485-91.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported

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