(E) -Crotonic acid

• Description :

  NSC 8751 (trans-2-Butenoic acid; trans-Crotonic acid) is an unsaturated carboxylic acid compound containing α, β-unsaturated carboxylic acid groups. NSC 8751 is one of the important analogs for evaluating the safety of fragrance ingredients and is used to evaluate the toxicological properties of compounds with similar structures. When NSC 8751 is applied to local lymph nodes, a 50% concentration does not cause skin sensitization. Structural analogs of NSC 8751 have been shown to be non-genotoxic. trans-Crotonic acid can be used in the preparation of cosmetics and food additives[1][2].

• Product Name Alternative :

  (E) -2-Butenoic acid; trans-2-Butenoic acid; trans-Crotonic acid

• UNSPSC :

  12352211

• Hazard Statement :

  H318

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/nsc-8751.html

• Purity :

  99.77

• Solubility :

  H2O : 25 mg/mL (ultrasonic)

• Smiles :

  C/C=C/C(O)=O

• Molecular Formula :

  C4H6O2

• Molecular Weight :

  86.09

• Precautions :

  H318

• References & Citations :

  [1]Api AM, et al. RIFM fragrance ingredient safety assessment 2-methyl-trans-2-butenoic acid, CAS Registry Number 80-59-1. Food Chem Toxicol. 2018 Sep;118 Suppl 1:S1-S7.|[2]Jasicka-Misiak I, et al. Crotonic acid as a bioactive factor in carrot seeds (Daucus carota L.) . Phytochemistry. 2005 Jun;66 (12) :1485-91.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [107-93-7]