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Ligustroflavone (Standard)

CAT: 0804-HY-N0546RSize: 1 EachDry Ice: NoHazardous: No
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Description
Ligustroflavone (Standard) is the analytical standard of Ligustroflavone. This product is intended for research and analytical applications. Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis[1][2][3].
CAS Number
260413-62-5
Product Name Alternative
Nuezhenoside (Standard)
UNSPSC
12352005
Target
CaSR; Mixed Lineage Kinase; Reference Standards; RIP kinase; TGF-beta/Smad
Type
Reference Standards
Related Pathways
Apoptosis; GPCR/G Protein; MAPK/ERK Pathway; Others; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Endocrinology; Metabolic Disease; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ligustroflavone-standard.html
Smiles
O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO[C@H](O[C@@H](C)[C@H](O)[C@H]3O)[C@@H]3O)[C@@H](O)[C@@H]4O)[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)=C6)C2=C6O
Molecular Formula
C33H40O18
Molecular Weight
724.66
References & Citations
[1]Feng R, et al. Protective Effects of Ligustroflavone, an Active Compound from Ligustrum lucidum, on Diabetes-Induced Osteoporosis in Mice: A Potential Candidate as Calcium-Sensing Receptor Antagonist. Am J Chin Med. 2019;47 (2) :457-476.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Isoform
RIPK1; RIPK3

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