AnnH31

CAT: 0804-HY-129449-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-129449-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM) . AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM. AnnH31 inhibits cell viability of HeLa, PC12 and SH-SY5Y cells[1].

CAS Number

241809-12-1

UNSPSC

12352005

Target

DYRK; Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/annh31.html

Purity

99.91

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

N#CCN1C2=C(C3=C1C=C(C=C3)OC)C=CN=C2C

Molecular Formula

C15H13N3O

Molecular Weight

251.28

References & Citations

[1]Rüben K, et al. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS One. 2015 Jul 20;10 (7) :e0132453.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Alternative Products

Catalog	Name
T26632-01	AnnH31
B3287-500	DIRK1A/1B inhibitor AnnH31
GW2289-500ug	DYRK1A/B Inhibitor AnnH31

AnnH31

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