DHEA

CAT: 0804-HY-14650-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-14650-01Size:500 mg
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Description
DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
CAS Number
[53-43-0]
Product Name Alternative
Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone
UNSPSC
12352211
Hazard Statement
H361
Target
Androgen Receptor; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Endocrinology; Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/DHEA.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic) |Ethanol : 40 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL
Smiles
O=C1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Molecular Formula
C19H28O2
Molecular Weight
288.42
Precautions
H361
References & Citations
[1]Anagnostopoulou V, et al. Differential effects of dehydroepiandrosterone and testosterone in prostate and colon cancer cell apoptosis: the role of nerve growth factor (NGF) receptors. Endocrinology. 2013 Jul;154 (7) :2446-56.|[2]McNelis JC, et al. Dehydroepiandrosterone exerts anti-glucocorticoid action on human preadipocyte proliferation, differentiation and glucose uptake. Am J Physiol Endocrinol Metab. 2013 Nov 1;305 (9) :E1134-44.|[3]Catalina F, et al. Decrease of core body temperature in mice by dehydroepiandrosterone. Exp Biol Med (Maywood) . 2002 Jun;227 (6) :382-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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