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UMB298

CAT: 0804-HY-139148-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139148-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UMB298 is a potent and selective CBP/P300 bromodomain inhibitor[1].
CAS Number
2266569-73-5
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/umb298.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC1=C(C2=CC3=NC(CCC4=CC=C(OC)C(Cl)=C4)=C(NC5CCCCC5)N3C=C2)C(C)=NO1
Molecular Formula
C27H31ClN4O2
Molecular Weight
479.01
References & Citations
[1]Muthengi A, et al. Development of Dimethylisoxazole-Attached Imidazo[1,2-a]pyridines as Potent and Selective CBP/P300 Inhibitors. J Med Chem. 2021;64 (9) :5787-5801.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4

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