(R)-Simurosertib

• UNSPSC Description:

  (R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib. Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of [1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/r-simurosertib.html

• Purity:

  99.58

• Solubility:

  DMSO : 75 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=C(N2)C=C(C3=CNN=C3C)S1)N=C2[C@H]4CC5CCN4CC5

• Molecular Weight:

  341.43

• References & Citations:

  [1]K Iwai, et al. A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity. European Journal of Cancer , 2016 , 69 (1) :S34.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1330782-69-8