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Anti-Hu CD93 APC

CAT: 0270-1A-794-T100Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0270-1A-794-T100Size:100 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD93 (also known as C1qR1) is a type I transmembrane glycoprotein containing extracellular N-terminal C-type lectin domain and five EGF-like domains, and an intracellular tail interacting with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. CD93 was reported to serve as a receptor for complement component C1q, but this function has not been fully elucidated yet. CD93 is involved in intercellular adhesion and in the clearance of apoptotic cells.
Certification
RUO
Reactivity
Human
Immunogen
KG1 cell line
Target Antigen
CD93
Clone
VIMD2
Applications
FC (QC tested)
Format
APC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Steinberger P, Szekeres A, Wille S, Stöckl J, Selenko N, Prager E, Staffler G, Madic O, Stockinger H, Knapp W: Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning. J Leukoc Biol. 2002 Jan;71 (1) :133-40., URL: http://www.ncbi.nlm.nih.gov/pubmed/11781389
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody VIMD2 recognizes an extracellular epitope on CD93, an approximately 110-120 kDa glycoprotein expressed mainly on myeloid cells and endothelial cells.
Applications Notes
6
Isotype
Mouse IgG1

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