Anti-Ms CD106 Purified Azide Free

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Alternative Products

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MBS1800176-01	Anti-Ms CD106 Purified
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MBS1801739-02	Anti-Ms CD106 Purified Azide Free
MBS1801739-01	Anti-Ms CD106 Purified Azide Free
MBS1800177-01	Anti-Ms CD106 FITC
MBS1800177-02	Anti-Ms CD106 FITC
MBS1800178-01	Anti-Ms CD106 PE
MBS1800178-02	Anti-Ms CD106 PE
E16FMU106-500U	Purified anti-mouse CD106
MBS1801552-02	Anti-Hu CD106 Purified

CAT:

270-10-742-C100

Size:

0.1 mg

Price:

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For price, please contact [email protected].

Anti-Ms CD106 Purified Azide Free

Background: CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.
Specifications: The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
Certification: RUO
Host: Rat
Species Reactivity: Mouse
Immunogen: Murine preadipose cell line PA6
Target Antigen: CD106
Isotype: IgG2a κ
Clone: 429 (MVCAM.A)
Applications: Flow cytometry: Recommended dilution: 1-4 µg/mL.Functional application: Blocking
Validated Applications: FC, IP, IHC-F, Functional assays
Concentration: 1 mg/mL
Format: Purified Azide Free
Buffer: Phosphate buffered saline (PBS), pH 7.4
References & Citations: *Lochhead RB, Sonderegger FL, Ma Y, Brewster JE, Cornwall D, Maylor-Hagen H, Miller JC, Zachary JF, Weis JH, Weis JJ: Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue. J Immunol. 2012 Sep 1189(5):2488-501., URL: https://www.ncbi.nlm.nih.gov/pubmed/22851707,*Dunzendorfer S, Lee HK, Soldau K, Tobias PS: Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses. FASEB J. 2004 Jul18(10):1117-9. Epub 2004 May 7., URL: http://www.ncbi.nlm.nih.gov/pubmed/15132988 ,*Sacher T, Knolle P, Nichterlein T, Arnold B, Hämmerling GJ, Limmer A: CpG-ODN-induced inflammation is sufficient to cause T-cell-mediated autoaggression against hepatocytes. Eur J Immunol. 2002 Dec32(12):3628-37., URL: https://www.ncbi.nlm.nih.gov/pubmed/12516551,
Storage Conditions: Store at 2-8°C. Do not freeze.

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Cat	Name
11-742-C025	Anti-Ms CD106 Purified
11-742-C100	Anti-Ms CD106 Purified
10-742-C100	Anti-Ms CD106 Purified Azide Free
1P-742-C025	Anti-Ms CD106 PE
1P-742-C100	Anti-Ms CD106 PE
1F-742-C100	Anti-Ms CD106 FITC
1F-742-C025	Anti-Ms CD106 FITC
11-606-C100	Anti-Hu CD106 Purified
11-606-C025	Anti-Hu CD106 Purified
11-569-C025	Anti-Ms Bim Purified