TRAIL Protein

• Gene Aliases:

  TL2, APO2L, CD253, TRAIL, Apo-2L, TNLG6A

• Gene ID:

  8743

• Accession Number:

  NP_003801.1

• Reactivity:

  Human

• Target:

  TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.

• Type:

  Protein

• Source:

  E. Coli

• Purification:

  The sTRAIL is purified by proprietary chromatographic techniques.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Bioactivity:

  50

• Format:

  Lyophilized// from a filtered (0.2μm) solution containing 20mM Tris-HCl pH 8.0 and 150mM NaCl Physical Appearance:// Sterile filtered white powderPhysical Appearance:// Sterile filtered white powder

• Molecular Weight:

  ~21 kDa

• Notes:

  Formerly GWB-63F4CF

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  TRAIL

• Protein Name:

  Tumor necrosis factor ligand superfamily member 10

• Gene Name URL:

  TRAIL